Microbiome Nourishing
Fifteen entries that feed or restore the organisms that keep the gut calm. My view, after a decade of watching: probiotics are often overhyped in IBD, and most of the trials disappoint, but the right organism for the right person can be important, which is why four organisms are highlighted here alongside the fibers that feed them. As a broad rule, probiotics are better tolerated and more effective in ulcerative colitis than in Crohn's, though people with either can benefit from them and be bothered by them. Whatever you introduce, introduce it gradually and let tolerance set the pace; that applies to the fibers as much as to the organisms. One entry, spore-based probiotics, is here so you know why I don't recommend it. If your diagnosis is microscopic colitis, note that the AGA guideline suggests against probiotics for inducing remission; in my own work I have seen selected organisms help some people with MC, and I hold that observation next to the guideline rather than against it.
In this chapter
D-01Akkermansia muciniphilaRead entry →D-02Saccharomyces boulardiiRead entry →D-03Spore-based probioticsRead entry →D-04Multi-strain Lactobacillus / BifidobacteriumRead entry →D-05Lactobacillus reuteriRead entry →D-06Lactobacillus plantarum 299vRead entry →D-07PsylliumRead entry →D-08Partially hydrolyzed guar gumRead entry →D-09Inulin / FOSRead entry →D-10Galacto-oligosaccharides (GOS)Read entry →D-11Resistant starchRead entry →D-12Larch arabinogalactanRead entry →D-13Acacia gumRead entry →D-14LactoferrinRead entry →D-15Beta-glucanRead entry →Why there is no spore-based probiotic here
Spore-forming Bacillus probiotics are popular and heavily marketed. In my judgment they are the wrong tool for an inflamed gut, spores germinate unpredictably, and I have seen too many flares follow them. Entry D-03 stays in the list so the question is answered; it carries no product on purpose.
Read on
Rebuilding after a course of antibiotics →The most missing bacterium →Fiber, fermentation and butyrate →READ & SHOP
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Microbiome Nourishing
Akkermansia muciniphila
The mucin-layer resident most consistently depleted in IBD, now available as a single-strain product for the first time. No IBD intervention trials yet, this is a…
Microbiome Nourishing
Saccharomyces boulardii
A probiotic yeast, not a bacterium, so antibiotics don't kill it. A small Italian trial (n = 32) found relapse in 6% of Crohn's patients on mesalamine plus S.…
Microbiome Nourishing
Lactobacillus plantarum 299v
Lactobacillus plantarum 299v is one of the best-characterized single probiotic strains: human-origin, acid- and bile-tolerant, and studied in randomized IBS trials…
Options to explore with your care team. These are not a recommendation to take them together. Andrew earns a commission on Fullscript purchases. US shipping only.




