M-04 · Sleep, Stress & Attention

L-tyrosine

l-tyrosine
M-04 · #bonus

L-tyrosine

Pure Encapsulations, l-Tyrosine · 90 caps
Sleep · stress · attention

The amino acid the brain turns into dopamine and noradrenaline. In randomized studies, tyrosine preserves working memory and attention when the dopamine system is under load: sleep loss, cold, multitasking, acute stress. There are no good trials in ADHD and none in IBD; the bridge to this guide is mechanistic, since inflammation lowers dopamine tone, which is part of why active disease feels like brain fog. Free-form, taken on an empty stomach so it is not crowded out by other amino acids.

Not with MAOI antidepressants or levodopa; caution with hyperthyroidism or Graves' disease; can raise blood pressure at high doses.
References 194–195
Andrew's notes

On an empty stomach, first thing in the morning, as needed. It does nothing for me taken with food. A slight lift in mood and concentration; it helps my ADHD. Secondary to everything else in this guide.

SKU
PUR-LTY9
Evidence2

RCTs under acute stress; none in ADHD or IBD

Andrew's score4

Andrew's judgment, 1–5.

L-tyrosine
L-tyrosine · C9H11NO3 · 181.2 g/mol · PubChem CID 6057

References

  1. Jongkees BJ, Hommel B, Kühn S, Colzato LS. Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands: a review. J Psychiatr Res 2015;70:50–57.
  2. Felger JC, Treadway MT. Inflammation effects on motivation and motor activity: role of dopamine. Neuropsychopharmacology 2017;42(1):216–241.

READ & SHOP

Explore related supplements

Browse all 100 →

Sleep, Stress & Attention

L-theanine

The amino acid that makes green tea calming. L-theanine raises alpha-wave activity in the brain within an hour, and in randomized trials it reduced stress-related…

Evidence 2/5Andrew 5/5

Options to explore with your care team. These are not a recommendation to take them together. Andrew earns a commission on Fullscript purchases. US shipping only.